Pencil!

Synfig Studio is a free and open-source 2D animation software, designed as powerful industrial-strength solution for creating film-quality animation using a vector and bitmap artwork.

This is software for producing a 2D animation.It is based on the software "Toonz", which was developed by Digital Video S.p.A. in Italy, customized by Studio Ghibli, and has been used for creating its works for many years. Dwango launches this OpenToonz project, in cooperation with Digital Video and Studio Ghibli.This software can be used by anyone free of charge, no matter whether the purpose of use is commercial or not.This is available as an open source, so that users can modify its source code freely.We aim to develop a new platform for connecting the academic research into frontline animation production. »

Karbon, component of Calligra Suite , is the scalable vector drawing application in KDE. It allows artists to create complex drawings without losing image quality when zooming in on, or resizing the drawing. Graphic design ideas can be quickly and easily transformed into high quality illustrations with Karbon.

Tupi is a design and authoring tool for digital artists interested in 2D Animation, fork of the KToon project, offering an interface experience focused on 8-100 years old kids.

Pencil2D is an opensource animation/drawing software for Mac OS X, Windows, and Linux, based on old Pencil software. It lets you create traditional hand-drawn animation (cartoon) using both bitmap and vector graphics.

Xara Designer Pro X10 is a fully integrated single package solution for all your graphic design needs, for print and the web. Illustration, photo editing, DTP and document creation, web graphics and websites - Designer Pro does it all!

InsightPoint is a cool multi-scene vector drawing tool for Windows and Linux.

sK1 is a powerful illustration program for the Linux platform that can substitute professional proprietary software like CorelDRAW or Adobe Illustrator.

Xara Photo & Graphic Designer (formerly Xara Xtreme) is quite simply the worlds fastest graphics software, with truly flexible illustration tools and revolutionary photo handling. A single application for all types of creative work.

QueekyPaint is a unique browser-based drawing tool for creating animated drawings online. Visit the massive gallerys and learn drawing by watching the process of your favourite artists. QueekyPaint is free and simple to use.

Creative Docs .NET is a vector-based graphic design tool with support for rich text, ideal to quickly write short documents, manuals, posters, illustrations, schemas, plans, flow charts, and much more.

Animation Paper is a software package for doing 2D animation. It will allow traditional animators to utilize the powerful and timesaving advantages of computers. Using PAP you see your animation as you create it, removing the need for line tests, cameras and scanners. After getting comfortable with drawing directly to the screen you never want to go back!

Vectorian Giotto is a simple flash animation software that allows you to create professional quality Flash animations for websites and other projects without coding.

Ella (an acronym for Elegant Light Linux Animator) is a light animation software intended to achieve a aim of the Linux world : a functionnal and WYSIWYG (What You See Is What You Get) 2D animation sofware.