xTerminator!

Use this program to "Unspam" your mailbox(es). The program can be integrated with the mail server to automatically filter all mail for a site. It can also be run by individual users on their own mailbox and integrates with several mail programs. SpamAssassin is highly configurable; if used as a system-wide filter it can still be configured to support per-user preferences.

Over 8 million people use MailWasher as their spam filter

Spam Reader is a free anti-spam add-on for Microsoft Outlook. The software uses the most reliable approach to block junk emails - Bayesian algorithm based on statistical analysis, capable to be adjusted to user's needs and detect up to 98% of spam messages. Spam Reader automatically scans all incoming mails and sends detected spam messages to the special folder for further review.

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SpamSieve is an extremely accurate and easy to use Bayesian spam filter for Mac e-mail programs. Macworld's "Software of the Year".

Most people find spam e-mails the biggest nuisance on the Internet. Today, spam e-mails account for over 80% of all e-mail traffic and their volumes increase daily. Strike back with BullGuard Spamfilter.

Postgrey is a Postfix policy server implementing greylisting developed by David Schweikert.