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MATLAB is a numerical computing environment and programming language. Maintained by The MathWorks, MATLAB allows easy matrix manipulation, plotting of functions and data, implementation of algorithms, creation of user interfaces, and interfacing with programs in other languages. Although it is numeric only, an optional toolbox uses the MuPAD symbolic engine, allowing access to computer algebra capabilities. An additional package, Simulink, adds graphical multidomain simulation and Model-Based Design for dynamic and embedded systems. »

SciPy (pronounced "Sigh Pie") is open-source software for mathematics, science, and engineering. It is also the name of a very popular conference on scientific programming with Python. The SciPy library depends on NumPy, which provides convenient and fast N-dimensional array manipulation.

Spyder (previously known as Pydee) is a free open-source Python development environment providing MATLAB-like features in a simple and light-weighted software, available for Windows XP/Vista/7, GNU/Linux and Mac OS X.

Scilab is a scientific software package for numerical computations providing a powerful open computing environment for engineering and scientific applications. Scilab is an open source software and includes hundreds of mathematical functions with the possibility to add interactively programs from various languages (C, C++, Fortran…).It has sophisticated data structures (including lists, polynomials, rational functions, linear systems...), an interpreter and a high level programming language.

FreeMat is an environment for rapid engineering and scientific processing. It is similar to commercial systems such as MATLAB from Mathworks and IDL from Research Systems, but is Open Source.

Xcos is a graphical editor to design hybrid dynamical systems models. Models can be designed, loaded, saved, compiled and simulated.

Graphical frontend for GNU Octave. Edit formulas in native mathematical notation. Available / tested for Linux x586 / x86_64, WinXP, Vista, and MacOS.

Reinteract is a system for interactive experimentation with Python. Reinteract worksheets contain Python code combined with the results of that code, formatted as text or graphical plots. Youu can go back and edit previously entered statements, and the results will update. Reinteract is suitable for experimentation with the Python language and for data analysis using the NumPy and SciPy packages.

CloudStat is the cloud environment for building statistical applications collaboratively.

Calculation Laboratory is an online environment for numerical computations. By using this site you get fast access to the easy-to-use tool for computing from anywhere. Calculation Lab is perfect for engineering students.

Derive 6.1: Powerful system for doing symbolic and numeric mathematics. This application is no longer available or supported.

Doronix Math Toolbox is a numerical computing environment with programming language which can be used as alternative to MATLAB. It allows matrix manipulations, plotting of functions and data, implementation of algorithms, creation of user functions, import and export CSV-files and more

Rodeo is a Python IDE for doing data science and analysis natively on your desktop.