Tweetbot!

TweetDeck aims to evolve the existing functionality of Twitter by taking an abundance of information i.e twitter feeds, and breaking it down into more manageable bite sized pieces. From a poster's point of view, it supports shortening URLs by a couple of different services, posting and hosting images at different sites, and scheduling tweets to be posted even if you're offline.

Tired of seeing ads and promotions in your timeline, being disrupted by tweets from bots and people you don't like, or just want a pure Twitter experience back like the good old days? Try Twidere for Twitter!

Choqok - KDE Micro-Blogging ClientThe name comes from an ancient Persian word, means Sparrow!Currently supports Twitter.com and Identi.ca services.It currently features:

Gwibber is an open source microblogging client for GNOME developed with Python and GTK. It brings the most popular social networking web services to your desktop and gives you the ability to control how you communicate.

Twitterrific is a fun application that lets you both read and publish posts or "tweets" to the Twitter community website. The applications user interface is clean, concise and designed to take up a minimum of real estate on your Mac or iOS device.

"Tweet It!" is designed with every single Windows device in mind. From phone with touch screen to desktop PC with mouse and keyboard you'll have great expirience. And Continuum support for pleasant PC like Twitter browsing when you are away from it.

Linux Twitter client designed for multiple columns of multiple accounts.

Fenice is a full-featured Twitter app for Windows designed to offer the best Twitter experience to every user (pro or casual ones).

Echofon: social apps for Twitter and Facebook.

Terminal-based Twitter Client with Streaming API support. Only supports Ruby 1.9 and later.

Flamingo is a bright and colourful Twitter client, which a simple and greatly customisable interface. It provides you with the Twitter experience you know and love with beautiful material design. You can easily switch between several accounts, and individually theme those accounts.* Previews for Instagram, Flickr, YouTube, Vine, Path.com & image URLs* GIFs can be played inline in the timeline and you can easily add them to your tweets (powered by Giphy).* Hover preview allows you to quickly preview photos, gifs and user profiles by simply long pressing on an icon or image. You can preview, zoom and pan the image all with one tap!* Insanely customisable, almost every part of the app can be changed to your liking* Other fun stuff including streaming, mutes, background syncing, scheduled tweets & many more! »

Socialite is a revolutionary social application that keeps all your social networks in one convenient place!Socialite makes it easy to stay in touch with the social networks and services that matter to you.

YoruFukurou (NightOwl) is a Twitter client for Mac OS X, designed for Twitter addicts. It provides powerful functionality through simple user interface.

Tweetdeckr is an open source TweetDeck replacement client.