Renoise!

LMMS is a free cross-platform alternative to commercial programs like FL Studio , which allow you to produce music with your computer. This includes the creation of melodies and beats, the synthesis and mixing of sounds, and arranging of samples. You can have fun with your MIDI-keyboard and much more; all in a user-friendly and modern interface.

Ardour is a hard disk recorder and digital audio workstation application. It runs on GNU/Linux, Mac OS X, and Windows. Ardour's intention is to provide digital audio workstation software suitable for professional use.

REAPER is a complete digital audio production application for Windows and OS X, offering a full multitrack audio and MIDI recording, editing, processing, mixing and mastering toolset.

Live is software for creating musical ideas, turning them into finished songs, and even taking them onto the stage.

Cubase is a computer program for music production/recording.The program offers recording, producing and mixing of sounds in order to make music production for distribution on CDs or the internet.

Logic Pro lets you translate musical inspiration into professional productions. A range of powerful, easy-to-use features puts sophisticated tools at your fingertips, and complete surround support lets you make incredible, immersive music.

OpenMPT (short hand for Open ModPlug Tracker) is a popular tracker software for Windows. OpenMPT is completely free and allows you to create and play back some great music on your computer. Based on the original ModPlug Tracker written by Olivier Lapicque, OpenMPT is free software and supports a wide variety of module formats and offers an intuitive, native GUI as well as advanced features such as VST plugins and ASIO output.

Bitwig Studio is a multi-platform music-creation system for production, performance and DJing, with a focus on flexible editing tools and a super-fast workflow.

MilkyTracker is an open source, multi-platform music application for creating .MOD and .XM module files. It attempts to recreate the module replay and user experience of the popular DOS program Fasttracker II, with special playback modes available for improved Amiga ProTracker 2/3 compatibility.

SunVox is a small, fast and powerful modular synthesizer with pattern based sequencer (tracker). It is a tool for those people who like to compose music wherever they are, whenever they wish. On any device. SunVox is available for desktop PC (Windows, Linux, Mac OS X), pocket computers (Windows Mobile, PalmOS, Maemo, iOS, Android) and netbooks.

ACID Pro 7 software is a DAW powerhouse that combines full multitrack recording and mixing, MIDI sequencing, and legendary ACID looping functionality for a seamless music-creation and post-production environment. More creative partner than production tool, ACID Pro 7 software inspires you like nothing else. With its Transparent Technology™ design, ACID Pro 7 software removes typical barriers to the creative workflow so you can effortlessly transform ideas into real results.

Psycle is a Music tracker (like FastTracker 2 or Impulse Tracker) combined with plugin modularity. It supports its own plugin API, the VST2 plugin standard, and a tracker style sampler playback.

Artists of all levels, from beginner to seasoned professional, will find Studio One a serious alternative to the intimidating, bloated offerings currently considered the standards. It's a groundbreaking music creation and production application for Mac OS X and Windows XP/Vista/7 that makes audio recording, MIDI sequencing, and audio mastering ridiculously simple right out of the box.