PostGIS!

GRASS GIS (Geographic Resources Analysis Support System) is an open source, free software (FOSS) Geographical Information System (GIS) with raster, topological, vector, image processing, and visualization functionality. Used for geospatial data management and analysis, image processing, graphics/maps production, spatial modeling, and visualization, GRASS is currently used in academic and commercial settings around the world, as well as by many governmental agencies and environmental consulting companies. »

SpatiaLite is a spatial extension to SQLite, providing vector geodatabase functionality. It is similar to PostGIS, Oracle Spatial, and SQL Server with spatial extensions, although SQLite/SpatiaLite aren't based on client-server architecture: they adopt a simpler personal architecture. i.e. the whole SQL engine is directly embedded within the application itself: a complete database simply is an ordinary file which can be freely copied (or even deleted) and transferred from one computer/OS to a different one without any special precaution. »

A location intelligence and visualization engine that empowers you to effortlessly transform data into insights. With CartoDB, connect and map location data, quickly customize your visualizations, and develop powerful location based apps.

ArcGIS is geographic information system (GIS) software for visualizing, managing, creating, and analyzing geographic data. Using ArcGIS, you can understand the geographic context of your data, allowing you to see relationships and identify patterns in new ways.

gvSIG is a Geographic Information System (GIS), that is, a desktop application designed for capturing, storing, handling, analyzing and deploying any kind of referenced geographic information in order to solve complex management and planning problems.

Mapline is the simplest mapping software on the planet! Be empowered with map visualizations from Excel spreadsheet data to optimize logistics, enhance market planning, identify growth opportunities, or mitigate market risks. Create your first map now!

H2GIS is a spatial extension of the H2 Database Engine in the spirit of PostGIS . It adds support for managing spatial features and operations including a Geometry constraints, the Open Geospatial Consortium (OGC) Simple Features for SQL (SFSQL) functions and additional spatial functions that we (the OrbisGIS team) develop.

MapInfo Professional is a powerful, functionally rich desktop mapping application from Pitney Bowes MapInfo, designed to enable organisations to solve business problems that have a geographical element.

Manifold GIS is a combination of mapping, CAD, DBMS and image processing. The hallmark of GIS is the power of using a visual interface to view, grab, analyze, manipulate and transform data that would not be comprehensible in classic row and column DBMS text presentations. Although many people use Manifold to create brilliant and compelling maps for presentations, the unique power of Manifold comes from the visual computing it makes possible with databases ranging from personal data to the largest, most sophisticated, enterprise-class databases. At far less than the price of a limited mapping tool like Google Earth Pro, Manifold delivers far more capability. »

Spotzi is a geographical data company that offers a Mapbuilder. This is an easy-to-use FREE online GIS/data mapping platform for businesses/professionals/students. Whether you're a experienced/less experienced user. With a short learning curve, people can immediately start with creating maps from data.

Intergraph is the leading global provider of engineering and geospatial software that enables customers to visualize complex data. Businesses and governments in more than 60 countries rely on Intergraph’s industry-specific software to organize vast amounts of data into understandable visual representations and actionable intelligence.

Easily Work With Location Data In Spreadsheets. GeoSheets lets you get comprehensive location lookup by state, neighborhood, and more with dead simple functions.

Business mapping software (geographic information system) that delivers affordable, easy-to-use, professional mapping tools for mapping in these sectors: franchising, health care, business, territories, site selection, sales, marketing, banking, more

MapServer is an Open Source platform for publishing spatial data and interactive mapping applications to the web. Originally developed in the mid-1990’s at the University of Minnesota, MapServer is released under an MIT-style license, and runs on all major platforms (Windows, Linux, Mac OS X).