Intelliremote!

EventGhost is an advanced, easy to use and extensible automation tool for MS Windows. It can use different input devices like infrared or wireless remote controls to trigger macros, that on their part control a computer and its attached hardware. So it can be used to control a Media-PC with a normal consumer remote. But its possible uses go much beyond this.

The most powerful remote control solution for the Mac®. Control more than 100 applications, virtual keyboard and mouse, presentations, media center software and important system settings right from your iPhone™, iPod® Touch, your Apple® Remote or one of the many other remote controls supported by Remote Buddy!

Made by Promixis, Girder is the award winning home and industrial automation software that allows users of all skill level to make advanced scripts and macros to automate many functions both on the computer and around the house or office. Based on the Lua scripting language, Girder is a graphical user interface that allows easy access to devices like lights, security systems, home theater, and any or all PCs functions including full application control for any program.