ENIGMA!

Unreal Engine is a professional suite of tools and technologies used for building high-quality games across a range of platforms. Unreal Engine’s rendering architecture enables developers to achieve stunning visuals and also scale elegantly to lower-end systems.

GDevelop is an open source game creation software, allowing to make games for the web (HTML5) or for Windows and Linux. No programming or coding skill is required! It is easy to use and powerful enough for advanced users.

Scirra Construct is a 2D game development engine with a focus on building games visually. No programming is required though the software uses a visual method for event handling that relies on programming concepts like variables, loops and conditions. It provides a powerful form of scripting that's as easy as clicking, dragging and dropping.

Adobe Animate, previously Adobe Flash Professional, is an authoring environment (IDE) that can produce interactive solutions for running inside web browsers or for the desktop.

Polycode's core is written in C++ and currently runs on Mac, Windows and Linux with iOS and Android support planned in the future. All platform-specific functionality is abstracted into a cross-platform core and implemented natively on each platform, so the same C++ code will compile on each supported platform out of the box.

Ren'Py is a free and cross-platform visual novel engine that helps you use words, pictures, and sounds to tell stories with the computer. Its easy and efficient script language makes it possible for non-programmers to make visual novels, while its Python support allows for complex simulation games.

cocos2d-x is a cross platform open source free 2D game engine for mobile gamedev, that is fast and stable, easy to learn and use.

Stencyl is the creator of StencylWorks, a tool that has enabled creators of all all skills levels create iOS and Flash games in no time. In 2012, Stencyl will expand into Android and HTML5 game publishing.

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Superpowers is an HTML5 development environment for making 2D and 3D games.It can be extended with plugins and lets you collaborate in real-time.

Urho3D is a lightweight, cross-platform rendering and game engine implemented in C++ and released under the MIT license. Greatly inspired by OGRE and Horde3D.