DHTMLX!

Ext JS is a JavaScript library for building interactive web applications using techniques such as Ajax, DHTML and DOM scripting. Ext includes interoperability with jQuery and Prototype.

Zepto is a minimalist JavaScript library for modern browsers with a largely jQuery-compatible API.

Intuitive and DocumentedIt is strongly influenced by jquery with many similar methods so you'll feel at ease developing with Umbrella.However there are also some improvements such as with .ajax(), .append(), etc.

MooTools (My Object-Oriented Tools) is a lightweight, object-oriented, web-application framework for JavaScript.

Dojo Toolkit is an open source modular JavaScript library (or more specifically JavaScript toolkit) designed to ease the rapid development of cross-platform, JavaScript/Ajax-based applications and web sites.

Enyo is a JavaScript app framework enabling developers build native-quality HTML5 apps that run everywhere — from phones and tablets to PCs and TVs.

qooxdoo is a universal JavaScript framework that enables you to create applications for a wide range of platforms. With its object-oriented programming model you build rich, interactive applications (RIAs), native-like apps for mobile devices, light-weight traditional web applications or even applications to run outside the browser.

No lock-in, no wrapper objectsDesigned to work with Vanilla JS, not replace it. Light as a featherOnly 3KB minified & gzipped!Chaining without prototype pollutionOnly adds one _ property (optional, customizable) ExtensibleAdding new blissful methods is easy as pie!(Mostly) readable sourceKnow what you’re running. Excellent for learning! Built with modern standardsUse polyfills to extend browser support.

FancyGrid is a professional product for any kind complexity: business analytics, CRUD applications, live data edit, tables(grids) for sites. FancyGrid is plugin-free library, it has no dependencies but integrated with jQuery, AngularJS. Its focus is on chart integration and server data communication.

Cx is a modern, multi-paradigm web framework inspired by React, Redux, Ext JS, Angular, D3 and other notable open-source libraries. Unlike most libraries which try to do just one thing and do it right, Cx tries to provide all necessary ingredients for building cool web applications. It is particularly convenient for building admin and dashboard applications as it includes a complete set of widgets with form elements, grids, navigation, charts, etc. There is support for inner (form) layouts and outer (app) layouts. The router is built-in if you’re building a single page application. Cx offers very powerful data-binding mechanisms, culture dependent formatting, view controllers and much more. The most important thing is that developing new widgets or modding existing widgets is easy, so each application developed using Cx can have a unique look and feel. »

AJS is a ultra lightweight JavaScript library that is around 2 years old. It is inspired by MochiKit, but differs by being small and expressive. The current version is only 33 KB (uncompressed!), whereas MochiKit and other libraries such as JQuery, Mootools or Prototype is over/around 100 KB.

JayData is a standards-based, cross-platform JavaScript library and a set of practices to access and manipulate data from various online and offline sources.