Allpix!

jUploadr is a cross platform, cross-site Photo uploader. Currently it runs on Windows Linux and OS X and supports both Flickr and Zooomr. It allows you to set all properties of a photo before you upload it. It also supports batch editing, so you can make short work of uploading a bunch of files.

Rightload is a small program that allows you to quickly upload files directly from a Windows folder to your server. Instead of using complicated software just to upload a few pictures, you just right-click on the files, select the server and target folder and Rightload will do the rest for you. Support for sites like Imageshack and Flickr out-of-the-box.

Postr is a Flickr uploading tool for the GNOME desktop, which aims to be simple to use but exposing enough of Flickr to be useful. It isn't finished yet, but its a very capable uploader already.

Frogr is a small application for the GNOME desktop that allows users to manage their accounts in the Flickr image hosting website. It supports all the basic Flickr features, including uploading pictures, adding descriptions, setting tags and managing sets and groups pools.

flickery lets you manage your Flickr photostream, photosets, groups, galleries, favorites and contacts with the ease of use of OS X.

Kflickr is an easy to use photo uploader for flickr written for KDE.

Photonic is a Flickr client for Mac OS X that let's you upload your photos to Flickr right from you Mac, without having to log into Flickr and upload photos by hand.

Upload and download your Flickr photos. photoSync is a desktop application that synchronizes your computer and Flickr account automatically.

Pure is a Flickr Client application* developed with content in mind. You can check your own feed, your favorite photos and the latest and most interesting photos uploaded.