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Twilio is a web-service API that lets you use your existing web languages and skills to build voice and SMS applications. We focus on building a simple, powerful, pay-as-you-go communications platform so that you can focus on what you do best.

Nexmo provides innovative communication APIs that bridge traditional voice and text services with cloud communications.

TokBox makes it easy to add video chat to your site or mobile application using either the OpenTok API or OpenTok Widgets. Supports WebRTC.

Plivo is a voice and SMS API platform that enables developers and enterprises to build powerful apps with great features. With 24/7 free tech support and low prices, Plivo can help your business scale globally.

The Hangouts API provides the programming interface to Hangouts video calls. It provides a JavaScript interface that enables your app to do such things as list the Hangout participants, share data between instances of your app in the Hangout, control some aspects of the user interface, and control the microphone, camera and speaker settings.

SightCall offers comprehensive real-time video APIs and Mobile SDKs that makes it simple to embed video calling and video conferencing into any application. SightCall provides a WebRTC Platform for healthcare, customer service and enterprise collaboration and has prepackaged integrations for Salesforce and Zimbra.

AddLive leverages WebRTC to allow anyone to easily add video and voice conferencing to their application.

If your reps or customers are remote, you should check out Blitzz.co.

engageSPARK enables anyone, anywhere to build and launch SMS and Voice Call messaging, surveying, and decision tree programs to 200+ countries – within minutes. It is a self-service website where any non-technical person can easily, quickly, and cheaply create messaging campaigns, curriculums, surveys, reminders, alerts, decision tree programs, etc. to send key information and collect important data from their participants.

SMS Messaging, Simplified.Compliant, reliable and scalable SMS infrastructure for business-critical transactional and marketing messages. Access over 400 million mobile consumers in emerging markets.