RetroArch!

ZSNES is a Super Nintendo Entertainment System emulator. Aside from emulation accuracy, many interface features first introduced in ZSNES have been adopted by other emulators. ZSNES interface features include: Smoothing and dynamic image scaling; screenshot capture; state saving; recording ZMV movies; increasing/decreasing game speed; ripping SPC700 sound files; integrated Game Genie\Pro Action Replay\GoldFinger cheat code support, decompression of JMA files; "NetPlay"; and GUI themes.

ePSXe (enhanced PSX emulator) is an emulator of the PlayStation video game console for x86-based PC hardware. ePSXe makes use of a plugin system to emulate GPU, SPU, and CD drive functions, similar to the model first introduced in PSEmu Pro.

VisualBoyAdvance (VBA) is a free software (GNU GPL) emulator targeted for the Game Boy, Super Game Boy, Game Boy Color, and Game Boy Advance handheld game consoles sold by Nintendo.

Project64 is a Nintendo 64 emulator for the Windows platform. It employs a plugin system that allows 3rd party developers to implement their own software. It is an emulator, meaning that the user has the option to run ROM files that can be extracted from a Nintendo 64 game cartridge.

ScummVM is a multi-platform interpreter that runs games using the SCUMM engine made by LucasArts which allows you to run classic graphical point-and-click adventure games, provided you have their data files.

Open Emu is an open source project to bring game emulation to OS X as a first class citizen, leveraging modern OS X technologies such as Cocoa, Core Animation and Quartz, and 3rd party libraries like Sparkle for auto-updating. Open Emu is based on a modular architecture, allowing for game-engine plugins, this means Open Emu can support a host of different emulation engines and back-ends while retaining a familiar OS X native front-end.

EmulationStation is a graphical and themeable emulator front-end that allows you to access all your favorite games in one place, even without a keyboard!

higan was formerly known as bsnes. The project was renamed after becoming a multi-system emulator.

Kega Fusion is an emulator for the Sega Genesis / Megadrive, Master System, Game Gear, 32x, SegaCD/MegaCD, SVP, Pico, SG-1000, SC-3000, and SF-7000 emulator for Win9x/ME/2000/XP/Vista/Win7, Mac OSX (Intel), and Linux.

Lakka is the official Linux distribution of RetroArch and the libretro ecosystem. Each game system is implemented as a libretro core, while the frontend RetroArch takes care of inputs and display.

The number one Game Boy Advance emulator for iOS is back, and has been rewritten from the ground up for iOS 7.