PikoPixel!

Aseprite (previously ASE, aka Allegro Sprite Editor) is a program to create animated sprites & pixel art. Sprites are little images that can be used in your website or in a video game. You can draw characters with movement, intros, textures, patterns, backgrounds, logos, color palettes, isometric levels, and more.

Remember the good old 2D games and their beautiful sprites? With Piskel you can create your own in a few clicks.

GrafX2 is a bitmap paint program inspired by the Amiga programs Deluxe Paint and Brilliance. Specialized in 256-color drawing, it includes a very large number of tools and effects that make it particularly suitable for pixel art, game graphics, and generally any detailed graphics painted with a mouse. The program is mostly developed on Linux and Windows, but is also portable on many other platforms.

Pixen is a pixel art editor designed for working with low-resolution raster art, such as those 8-bit sprites found in old-school video games. With innovative features like a color palette system, patterns, and high-zoom support, Pixen packs all the tools pixel artists need in an intuitive, Mac-native interface. Pixen also makes creating frame-by-frame animations fun and easy.

Pixelsque's goal is to be as simple as possible, while still retaining many powerful features. It works like any standard pixel art editor, with a pen, eraser, and shapes. Pinch zoom and two finger drag can be used to move around the image from anywhere. Lesser-used functions such as save/open/new, and others can be found in the menu, saving valuble screen space on phones, and allowing easy access on tablets. It fully supports all Android devices from low-end phones to high-end tablets.

Dotpict is a simple, intuitive and effective pixel art editor designed for mobile use.

Poxi is a browser-based, pixel art editor