Meteor!

GUN is an open source, realtime, graph database written entirely in JavaScript and built using peer-to-peer algorithms, making it surprisingly fault tolerant and easy to get started with.

Fast, unopinionated, minimalist web framework for Node.js

Polymer is a library that uses the latest web technologies to let you create custom HTML elements. Build anything from a button to a complete application as an encapsulated, reusable element that works across desktop and mobile.

Build incredible real-time applications in record time. Feathers is a real-time, micro-service web framework for NodeJS that gives you control over your data via RESTful resources, sockets and flexible plug-ins.

An open protocol for per-user storage

Sails.js make it easy to build custom, enterprise-grade Node.js apps. It is designed to mimic the MVC pattern of frameworks like Ruby on Rails, but with support for the requirements of modern apps: data-driven APIs with scalable, service-oriented architecture. It's especially good for building chat, realtime dashboards, or multiplayer games.

Forward-thinkingWritten with ES2016. Integrates with Web Components. No external dependencies except polyfills. Leverage the technology of the future but target today's mobile, desktop and browser environments.

Knockout is a JavaScript library that helps you to create rich, responsive display and editor user interfaces with a clean underlying data model. Any time you have sections of UI that update dynamically (e.g., changing depending on the user’s actions or when an external data source changes), KO can help you implement it more simply and maintainably.

A secure realtime server, supporting data-sync, RPCs and events

Durandal is a cross-device, cross-platform client framework written in JavaScript and designed to make Single Page Applications (SPAs) easy to create and maintain.